# NUMBER of proteins with Oi-value 6714 # NUMBER of proteins in calculation 2037 # TOTAL MOLECULES 8148000 (based on average of 4000 molecules per protein) # ID OI_VALUE PROTEINPROPHET_PROBABILITY TOTAL_SPECTRAL_COUNTS APEX_PROTEIN_ABUNDANCE NUMBER_OF_DEGENERATE_PROTEINS IDS_DEGENERATE_PROTEINS ANNOTATION YJR111C 8.08 0.84 4 581.3435 1 YJR111C YJR111C SGDID:S000003872,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria, Chr X from 636622-635771, reverse complement, Uncharacterized ORF YFR040W 38.708 0.89 12 385.7229 1 YFR040W SAP155 SGDID:S000001936,Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p, Chr VI from 234229-237237, Verified ORF YPL150W 35.21 0.74 1 29.3812 1 YPL150W YPL150W SGDID:S000006071,Hypothetical protein, Chr XVI from 268187-270892, Uncharacterized ORF YNL074C 13.34 1.00 5 523.9852 1 YNL074C MLF3 SGDID:S000005018,Serine-rich protein of unknown function; overproduction suppresses the growth inhibition caused by exposure to the immunosuppressant leflunomide, Chr XIV from 488125-486767, reverse complement, Verified ORF YCR088W 26.97 1.00 144 7464.2548 1 YCR088W ABP1 SGDID:S000000684,Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2\3 complex that plays a key role actin in cytoskeleton organization, Chr III from 265065-266843, Verified ORF YIL115C 63.178 1.00 7 154.8948 1 YIL115C NUP159 SGDID:S000001377,Subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side, forms a subcomplex with Nup82p and Nsp1p, required for mRNA export, Chr IX from 148706-144324, reverse complement, Verified ORF YOL138C 45.158 1.00 7 216.7046 1 YOL138C YOL138C SGDID:S000005498,Hypothetical protein, Chr XV from 65350-61325, reverse complement, Uncharacterized ORF YBR267W 12.969 0.99 3 320.151 1 YBR267W REI1 SGDID:S000000471,Protein of unknown function involved in bud growth in the mitotic signaling network; proposed negative regulator of Swe1p and Gin4p; contains dispersed C2H2 zinc finger domains, Chr II from 739836-741017, Verified ORF YNL044W 5.07 1.00 10 2757.3821 1 YNL044W YIP3 SGDID:S000004989,Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p, Chr XIV from 545269-545292,545372-545878, Verified ORF YDR395W 26.91 1.00 19 987.0628 1 YDR395W SXM1 SGDID:S000002803,Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1, Chr IV from 1263316-1266150, Verified ORF YGL133W 57.888 0.95 10 229.4245 1 YGL133W ITC1 SGDID:S000003101,Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1, Chr VII from 257712-261506, Verified ORF YGR129W 10.66 1.00 6 786.8626 1 YGR129W SYF2 SGDID:S000003361,Component of the spliceosome complex involved in pre-mRNA splicing; involved in regulation of cell cycle progression, Chr VII from 750405-751052, Verified ORF YER067W 4.44 0.84 8 2115.8808 1 YER067W YER067W SGDID:S000000869,Hypothetical protein, Chr V from 292064-292549, Uncharacterized ORF YGL067W 12.76 0.90 1 98.6045 1 YGL067W NPY1 SGDID:S000003035,NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes, Chr VII from 376104-377258, Verified ORF YCL050C 10.53 1.00 56 7434.7191 1 YCL050C APA1 SGDID:S000000555,Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p, Chr III from 38801-37836, reverse complement, Verified ORF YML048W 18.597 1.00 5 375.8651 1 YML048W GSF2 SGDID:S000004511,ER localized integral membrane protein that may promote secretion of certain hexose transporters, including Gal2p; involved in glucose-dependent repression, Chr XIII from 178426-179637, Verified ORF YCL043C 23.119 1.00 187 11307.7832 1 YCL043C PDI1 SGDID:S000000548,Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds, Chr III from 50221-48653, reverse complement, Verified ORF YNR035C 13.58 1.00 21 2161.8444 1 YNR035C ARC35 SGDID:S000005318,Subunit of the ARP2\3 complex, which is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin, Chr XIV from 694049-693021, reverse complement, Verified ORF YBR130C 17.18 0.97 7 552.5244 1 YBR130C SHE3 SGDID:S000000334,Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance, Chr II from 496863-495586, reverse complement, Verified ORF YOL014W 2 0.95 10 6640.4654 1 YOL014W YOL014W SGDID:S000005374,Hypothetical protein, Chr XV from 299694-300068, Uncharacterized ORF YLR057W 42.454 0.93 3 91.8735 1 YLR057W YLR057W SGDID:S000004047,Putative protein of unknown function; YLR050C is not an essential gene, Chr XII from 255307-257856, Uncharacterized ORF YFR034C 9.022 0.85 1 131.7106 1 YFR034C PHO4 SGDID:S000001930,Basic helix-loop-helix (bHLH) transcription factor; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability, Chr VI from 225946-225008, reverse complement, Verified ORF YPR072W 24.278 0.89 2 102.4972 1 YPR072W NOT5 SGDID:S000006276,Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation, Chr XVI from 690104-691786, Verified ORF YMR092C 23.7 1.00 15 884.8055 1 YMR092C AIP1 SGDID:S000004698,Actin cortical patch component, interacts with the actin depolymerizing factor cofilin; required to restrict cofilin localization to cortical patches; contains WD repeats, Chr XIII from 453478-451631, reverse complement, Verified ORF YOR232W 14.065 1.00 23 2286.0883 1 YOR232W MGE1 SGDID:S000005758,Protein of the mitochondrial matrix involved in protein import into mitochondria; acts as a cochaperone and a nucleotide release factor for Ssc1p; homolog of E. coli GrpE, Chr XV from 774574-775260, Verified ORF YGL021W 35.324 0.99 7 274.2636 1 YGL021W ALK1 SGDID:S000002989,Putative Ser-Thr protein kinase, belongs to the haspin family of kinases; contains a leucine zipper motif; may function in mitosis, Chr VII from 454790-457072, Verified ORF YHL034C 13.47 1.00 61 6330.9247 1 YHL034C SBP1 SGDID:S000001026,Nucleolar single-strand nucleic acid binding protein; associates with small nuclear RNAs, Chr VIII from 34075-33191, reverse complement, Verified ORF YDR418W 7.88 1.00 209 37078.7411 2 YDR418W,YEL054C RPL12B SGDID:S000002826,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins, Chr IV from 1301608-1302105, Verified ORF YOR317W 28.619 1.00 34 1660.846 1 YOR317W FAA1 SGDID:S000005844,Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; localized to both lipid particles and mitochondrial outer membrane; essential for stationary phase, Chr XV from 909340-911442, Verified ORF YGR162W 37.4 1.00 23 859.7281 1 YGR162W TIF4631 SGDID:S000003394,Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p, Chr VII from 824064-826922, Verified ORF YOR109W 44.484 1.00 9 282.8417 1 YOR109W INP53 SGDID:S000005635,Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in a TGN (trans Golgi network)-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches, Chr XV from 525279-528602, Verified ORF YKL193C 15.73 0.91 1 80.8756 1 YKL193C SDS22 SGDID:S000001676,Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis, Chr XI from 79887-78871, reverse complement, Verified ORF YKR090W 32.138 0.98 1 42.6296 1 YKR090W PXL1 SGDID:S000001798,LIM domain-containing protein that localizes to sites of polarized growth, required for selection and\or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin, Chr XI from 608588-610708, Verified ORF YDL066W 23.84 1.00 72 4222.1256 1 YDL066W IDP1 SGDID:S000002224,Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes, Chr IV from 334835-336121, Verified ORF YOR162C 32.41 0.98 4 169.0876 1 YOR162C YRR1 SGDID:S000005688,Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes, Chr XV from 641993-639561, reverse complement, Verified ORF YDL166C 11.39 0.75 8 736.4316 1 YDL166C FAP7 SGDID:S000002325,Essential NTPase required for small ribosome subunit synthesis, mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p, may be the endonuclease for site D, Chr IV from 164043-163450, reverse complement, Verified ORF YGL070C 3.89 0.98 1 352.1935 1 YGL070C RPB9 SGDID:S000003038,RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance, Chr VII from 374830-374462, reverse complement, Verified ORF YJL200C 31.209 1.00 24 1075.0689 1 YJL200C ACO2 SGDID:S000003736,Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol, Chr X from 58813-56444, reverse complement, Uncharacterized ORF YBR249C 11.49 1.00 58 7056.8823 1 YBR249C ARO4 SGDID:S000000453,3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine, Chr II from 717989-716877, reverse complement, Verified ORF YKL010C 49.676 1.00 11 309.5643 1 YKL010C UFD4 SGDID:S000001493,Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins, Chr XI from 425518-421067, reverse complement, Verified ORF YLR045C 38.189 0.99 3 108.7234 1 YLR045C STU2 SGDID:S000004035,Microtubule-associated protein (MAP) of the XMAP215\Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p, Chr XII from 237704-235038, reverse complement, Verified ORF YJL076W 52.018 1.00 10 268.7517 1 YJL076W NET1 SGDID:S000003612,Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure, Chr X from 295162-298731, Verified ORF YPL183C 51.394 1.00 34 924.8502 1 YPL183C YPL183C SGDID:S000006104,Hypothetical protein, Chr XVI from 202535-199494, reverse complement, Uncharacterized ORF YGR003W 35.059 1.00 5 199.3771 1 YGR003W CUL3 SGDID:S000003235,Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; null mutation has no apparent phenotype, Chr VII from 500136-502370, Verified ORF YDL111C 6.09 0.98 1 224.9643 1 YDL111C RRP42 SGDID:S000002269,Protein involved in rRNA processing; component of the exosome 3- 5 exonuclease complex with Rrp4p, Rrp41p, Rrp43p and Dis3p, Chr IV from 264110-263313, reverse complement, Verified ORF YPR148C 20.81 1.00 10 671.7889 1 YPR148C YPR148C SGDID:S000006352,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr XVI from 828136-826829, reverse complement, Uncharacterized ORF YMR131C 16.73 1.00 10 835.6202 1 YMR131C RRB1 SGDID:S000004738,Essential nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p, Chr XIII from 534697-533162, reverse complement, Verified ORF YMR109W 42.679 1.00 17 556.8517 1 YMR109W MYO5 SGDID:S000004715,One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization, Chr XIII from 486586-490245, Verified ORF YGR271W 82.277 1.00 6 101.9477 1 YGR271W SLH1 SGDID:S000003503,Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses, Chr VII from 1031797-1037700, Verified ORF YNL251C 17.5 0.99 3 237.2593 1 YNL251C NRD1 SGDID:S000005195,RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), required for transcription termination and 3' end maturation of nonpolyadenylated RNAs, Chr XIV from 174316-172589, reverse complement, Verified ORF YGL060W 21.7 0.66 2 85.0391 1 YGL060W YBP2 SGDID:S000003028,Protein with a role in resistance to oxidative stress; has similarity to Ybp1p, which is involved in regulation of the transcription factor Yap1p via oxidation of specific cysteine residues, Chr VII from 390070-391995, Verified ORF YMR310C 10.39 0.94 2 252.9572 1 YMR310C YMR310C SGDID:S000004927,Hypothetical protein, Chr XIII from 896668-895715, reverse complement, Uncharacterized ORF YGR173W 18.59 1.00 11 827.2146 1 YGR173W RBG2 SGDID:S000003405,Protein with similarity to mammalian developmentally regulated GTP-binding protein, Chr VII from 843859-844965, Uncharacterized ORF YOL151W 19.737 0.98 1 69.4144 1 YOL151W GRE2 SGDID:S000005511,NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway, Chr XV from 43693-44721, Verified ORF YLR362W 22.947 0.99 6 361.8807 1 YLR362W STE11 SGDID:S000004354,Signal transducing MEK kinase involved in pheromone response and pseudohyphal\invasive growth pathways, where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p, Chr XII from 849865-852018, Verified ORF YBR252W 5.14 0.93 5 1264.721 1 YBR252W DUT1 SGDID:S000000456,dUTPase, catalyzes the hydrolysis of dUTP to dUMP and PPi and thereby prevents the incorporation of uracil into DNA during replication, Chr II from 722606-723049, Verified ORF YMR105C 27.46 0.99 8 403.2083 1 YMR105C PGM2 SGDID:S000004711,Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase, Chr XIII from 477605-475896, reverse complement, Verified ORF YKL032C 6.45 0.70 1 151.7201 1 YKL032C IXR1 SGDID:S000001515,Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b, Chr XI from 381501-379708, reverse complement, Verified ORF YBR086C 27.038 0.93 4 192.3416 1 YBR086C IST2 SGDID:S000000290,Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process, Chr II from 423035-420195, reverse complement, Verified ORF YPL262W 16.54 1.00 28 2366.614 1 YPL262W FUM1 SGDID:S000006183,Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation, Chr XVI from 47336-48802, Verified ORF YKL168C 27.85 0.76 1 38.1498 1 YKL168C KKQ8 SGDID:S000001651,Putative serine\threonine protein kinase with unknown cellular role, Chr XI from 133497-131293, reverse complement, Verified ORF YLR361C-A 3.77 0.99 8 2936.8971 1 YLR361C-A YLR361C-A SGDID:S000028845,Identified by expression profiling and mass spectrometry, Chr XII from 849678-849382, reverse complement, Uncharacterized ORF YDL202W 14.449 1.00 5 483.7679 1 YDL202W MRPL11 SGDID:S000002361,Mitochondrial ribosomal protein of the large subunit, Chr IV from 98476-99225, Verified ORF YDR104C 57.78 1.00 6 145.1705 1 YDR104C SPO71 SGDID:S000002511,Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis, Chr IV from 664907-661170, reverse complement, Verified ORF YOR027W 33.099 1.00 190 8024.9741 1 YOR027W STI1 SGDID:S000005553,Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein, Chr XV from 381053-382822, Verified ORF YJL123C 26.588 1.00 24 1261.9161 1 YJL123C YJL123C SGDID:S000003659,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); YJL123C is a non-essential gene, Chr X from 189361-187925, reverse complement, Uncharacterized ORF YER075C 33.67 0.94 2 78.0584 1 YER075C PTP3 SGDID:S000000877,Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm, Chr V from 311195-308409, reverse complement, Verified ORF YMR086W 37.407 0.81 3 90.8151 1 YMR086W YMR086W SGDID:S000004692,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, Chr XIII from 439207-442089, Uncharacterized ORF YDR134C 0.64 0.97 10 21188.3272 2 YLR110C,YDR134C YDR134C SGDID:S000002541,Hypothetical protein, Chr IV from 721478-721068, reverse complement, pseudogene YNL071W 21.29 1.00 67 4399.5074 1 YNL071W LAT1 SGDID:S000005015,Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA, Chr XIV from 491524-492972, Verified ORF YBR221C 15.57 1.00 41 3681.291 1 YBR221C PDB1 SGDID:S000000425,E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved multi-protein complex found in mitochondria, Chr II from 666248-665148, reverse complement, Verified ORF YBL086C 20.82 0.96 8 515.686 1 YBL086C YBL086C SGDID:S000000182,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, Chr II from 62599-61199, reverse complement, Uncharacterized ORF YGL006W 44.118 0.88 8 223.0805 1 YGL006W PMC1 SGDID:S000002974,Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium, Chr VII from 485925-489446, Verified ORF YKL204W 18.61 0.85 1 63.8524 1 YKL204W EAP1 SGDID:S000001687,eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade, Chr XI from 53705-55603, Verified ORF YHR051W 9.33 0.67 6 602.3505 1 YHR051W COX6 SGDID:S000001093,Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels, Chr VIII from 209699-210145, Verified ORF YPL171C 15.25 0.83 2 152.1749 1 YPL171C OYE3 SGDID:S000006092,Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism, Chr XVI from 227370-226168, reverse complement, Verified ORF YDL116W 27.98 0.86 9 386.7213 1 YDL116W NUP84 SGDID:S000002274,Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis, Chr IV from 251566-253746, Verified ORF YPR124W 11.688 1.00 12 1435.3108 1 YPR124W CTR1 SGDID:S000006328,High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels, Chr XVI from 786204-787424, Verified ORF YGL167C 28.099 1.00 22 1094.5528 1 YGL167C PMR1 SGDID:S000003135,High affinity Ca2+\Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease, Chr VII from 190474-187622, reverse complement, Verified ORF YHR119W 45.49 1.00 13 399.5142 1 YHR119W SET1 SGDID:S000001161,Histone methyltransferase, subunit of the COMPASS (Set1C) complex which methylates histone H3 on lysine 4; required in transcriptional silencing near telomeres and at the silent mating type loci; contains a SET domain, Chr VIII from 346046-349288, Verified ORF YLL054C 30.205 0.99 11 504.0271 1 YLL054C YLL054C SGDID:S000003977,Putative protein of unknown function with similarity to Pip2p, an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene, Chr XII from 35203-32894, reverse complement, Uncharacterized ORF YDL055C 16.828 1.00 318 26417.9752 1 YDL055C PSA1 SGDID:S000002213,GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure, Chr IV from 356759-355674, reverse complement, Verified ORF YNL307C 15.4 1.00 5 453.8937 1 YNL307C MCK1 SGDID:S000005251,Protein serine\threonine\tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family, Chr XIV from 57573-56446, reverse complement, Verified ORF YDR378C 6.17 1.00 10 2265.7904 1 YDR378C LSM6 SGDID:S000002786,Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA, Chr IV from 1229601-1229341, reverse complement, Verified ORF YPR080W 16.899 1.00 1017 84132.7063 2 YBR118W,YPR080W TEF1 SGDID:S000006284,Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes, Chr XVI from 700592-701968, Verified ORF YOL019W 20.51 0.95 1 64.7534 1 YOL019W YOL019W SGDID:S000005379,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole, Chr XV from 288899-290554, Uncharacterized ORF YGR240C 39.77 1.00 382 13428.0418 1 YGR240C PFK1 SGDID:S000003472,Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes, Chr VII from 973739-970776, reverse complement, Verified ORF YMR295C 2.7 0.99 8 4100.7786 1 YMR295C YMR295C SGDID:S000004910,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud, Chr XIII from 858889-858296, reverse complement, Uncharacterized ORF YDR472W 12.77 1.00 3 328.4242 1 YDR472W TRS31 SGDID:S000002880,One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic, Chr IV from 1403314-1404165, Verified ORF YHL033C 9.32 1.00 326 48899.7456 1 YHL033C RPL8A SGDID:S000001025,Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits, Chr VIII from 36023-35253, reverse complement, Verified ORF YIL142W 28.682 1.00 42 2047.1269 1 YIL142W CCT2 SGDID:S000001404,Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo, Chr IX from 83302-84885, Verified ORF YJR048W 6.85 1.00 3 612.2595 2 YJR048W,YEL039C CYC1 SGDID:S000003809,Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration, Chr X from 526250-526579, Verified ORF YLR052W 11.098 0.99 1 124.7083 1 YLR052W IES3 SGDID:S000004042,Subunit of the INO80 chromatin remodeling complex, Chr XII from 247202-247954, Verified ORF YER052C 21.666 1.00 16 1032.3956 1 YER052C HOM3 SGDID:S000000854,Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis, Chr V from 257957-256374, reverse complement, Verified ORF YPR004C 15.179 1.00 9 828.904 1 YPR004C YPR004C SGDID:S000006208,Electron transfer flavoprotein complex subunit ETF-alpha; contains a FAD binding domain; interacts with YFH1, the yeast frataxin homolog, Chr XVI from 565038-564004, reverse complement, Verified ORF YPR187W 4.67 1.00 14 4190.9846 1 YPR187W RPO26 SGDID:S000006391,RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit, Chr XVI from 911253-911272,911349-911796, Verified ORF YOR230W 14.93 1.00 41 3839.0959 1 YOR230W WTM1 SGDID:S000005756,Transcriptional repressor involved in regulation of meiosis and silencing; contains WD repeats, Chr XV from 770801-772114, Verified ORF YOL141W 32.339 0.71 5 153.464 1 YOL141W PPM2 SGDID:S000005501,Putative carboxyl methyl transferase, has similarity to Ppm1p but biochemical activity not yet demonstrated, Chr XV from 56451-58538, Verified ORF YBR062C 4.45 0.76 2 477.5166 1 YBR062C YBR062C SGDID:S000000266,Hypothetical protein, Chr II from 366598-366583,366500-365974, reverse complement, Uncharacterized ORF YBR169C 38.18 1.00 40 1464.6335 1 YBR169C SSE2 SGDID:S000000373,Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p, Chr II from 575991-573910, reverse complement, Verified ORF YMR031C 46.757 1.00 15 448.4866 1 YMR031C YMR031C SGDID:S000004633,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern, Chr XIII from 334742-332211, reverse complement, Uncharacterized ORF YMR285C 26.548 0.98 2 103.2117 1 YMR285C NGL2 SGDID:S000004898,Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p and Ngl3p, Chr XIII from 841690-840143, reverse complement, Verified ORF YBR279W 25.26 1.00 11 608.7854 1 YBR279W PAF1 SGDID:S000000483,RNA polymerase II-associated protein, defines a large complex that is biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme and is required for full expression of a subset of cell cycle-regulated genes, Chr II from 761253-762590, Verified ORF YJL221C 26.51 0.99 4 208.8287 4 YJL221C,YIL172C,YGR287C,YOL157C FSP2 SGDID:S000003757,Protein of unknown function, expression is induced during nitrogen limitation, Chr X from 18536-16767, reverse complement, Verified ORF YER096W 21.41 0.94 7 429.6493 1 YER096W SHC1 SGDID:S000000898,Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH, Chr V from 351694-353232, Verified ORF YPL263C 24.27 1.00 4 230.4067 1 YPL263C KEL3 SGDID:S000006184,Cytoplasmic protein of unknown function, Chr XVI from 46506-44551, reverse complement, Verified ORF YIL128W 48.61 1.00 12 345.1123 1 YIL128W MET18 SGDID:S000001390,DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance, Chr IX from 113806-116904, Verified ORF YGR266W 30.2 0.98 4 181.4613 1 YGR266W YGR266W SGDID:S000003498,Protein of unknown function, predicted to contain a single transmembrane domain; localized to both the mitochondrial outer membrane and the plasma membrane, Chr VII from 1022662-1024767, Verified ORF YLR443W 10.77 0.97 2 251.8204 1 YLR443W ECM7 SGDID:S000004435,Non-essential protein of unknown function, Chr XII from 1022622-1023968, Verified ORF YHR155W 58.36 0.97 15 348.5399 1 YHR155W YSP1 SGDID:S000001198,Mitochondrial protein with a potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone, Chr VIII from 407106-410792, Uncharacterized ORF YER070W 28.3 1.00 49 2420.5527 1 YER070W RNR1 SGDID:S000000872,Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits, Chr V from 298948-301614, Verified ORF YNR043W 18.59 1.00 64 4812.8851 1 YNR043W MVD1 SGDID:S000005326,Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer, Chr XIV from 701897-703087, Verified ORF YLR083C 18.55 1.00 5 376.8174 1 YLR083C EMP70 SGDID:S000004073,Protein whose 24kDa cleavage product is found in endosome-enriched membrane fractions, predicted to be a transmembrane protein, Chr XII from 296095-294092, reverse complement, Verified ORF YKL056C 6.19 1.00 191 43136.7707 1 YKL056C YKL056C SGDID:S000001539,Protein of unknown function; putative ribosomal protein; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YKL056C is not an essential gene, Chr XI from 334559-334056, reverse complement, Verified ORF YGR082W 7.06 0.99 5 980.179 1 YGR082W TOM20 SGDID:S000003314,Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins, Chr VII from 644048-644599, Verified ORF YBR014C 10.328 0.94 3 381.7137 1 YBR014C YBR014C SGDID:S000000218,Hypothetical protein, Chr II from 267336-266725, reverse complement, Uncharacterized ORF YPL037C 6.49 1.00 210 45235.512 1 YPL037C EGD1 SGDID:S000005958,Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b, Chr XVI from 481898-481425, reverse complement, Verified ORF YOL039W 6.66 1.00 168 35264.6814 1 YOL039W RPP2A SGDID:S000005399,Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm, Chr XV from 254296-254616, Verified ORF YGL068W 8 1.00 22 3844.48 1 YGL068W MNP1 SGDID:S000003036,Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with similarity to E. coli L7\L12 ribosomal protein; required for normal respiratory growth, Chr VII from 375090-375674, Verified ORF YLR447C 11.31 1.00 18 2224.9221 1 YLR447C VMA6 SGDID:S000004439,Subunit D of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found in the endomembrane system; stabilizes VO subunits; required for V1 domain assembly on the vacuolar membrane, Chr XII from 1027890-1026853, reverse complement, Verified ORF YGL014W 19.45 0.78 2 112.1269 1 YGL014W PUF4 SGDID:S000002982,Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors, Chr VII from 466146-468812, Verified ORF YNL209W 20.4 1.00 1401 96009.2065 1 YNL209W SSB2 SGDID:S000005153,Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1, Chr XIV from 252060-253901, Verified ORF YMR113W 14.91 0.91 4 341.2939 1 YMR113W FOL3 SGDID:S000004719,Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis, Chr XIII from 494998-496281, Verified ORF YDR037W 27.06 1.00 264 13638.9534 1 YDR037W KRS1 SGDID:S000002444,Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis , Chr IV from 525437-527212, Verified ORF YMR217W 22.537 1.00 163 10111.0535 1 YMR217W GUA1 SGDID:S000004830,GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation, Chr XIII from 701789-703366, Verified ORF YOR007C 19.7 1.00 79 5606.1637 1 YOR007C SGT2 SGDID:S000005533,Glutamine-rich cytoplasmic protein of unknown function, contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions; conserved in human and C. elegans, Chr XV from 339979-338939, reverse complement, Verified ORF YPR016C 4.57 1.00 24 7341.7561 1 YPR016C TIF6 SGDID:S000006220,Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits, Chr XVI from 593066-592329, reverse complement, Verified ORF YMR296C 14.87 1.00 14 1316.2002 1 YMR296C LCB1 SGDID:S000004911,Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine, Chr XIII from 860890-859214, reverse complement, Verified ORF YDR182W 10.75 1.00 4 520.1833 1 YDR182W CDC1 SGDID:S000002590,Putative membrane protein of unknown function involved in Mn2+ homeostasis; mutants display actin and general growth defects, heterogeneous cell cycle arrests, and pleiotropic defects in cell cycle progression and organelle distribution, Chr IV from 827579-829054, Verified ORF YLR060W 26.22 1.00 180 9597.204 1 YLR060W FRS1 SGDID:S000004050,Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate the active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar, Chr XII from 260980-262767, Verified ORF YNL178W 17.75 1.00 521 41034.04 1 YNL178W RPS3 SGDID:S000005122,Protein component of the small (40S) ribosomal subunit, has apurinic\apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins, Chr XIV from 302682-303404, Verified ORF YML074C 10.41 1.00 44 5908.9029 1 YML074C FPR3 SGDID:S000004539,Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p, Chr XIII from 121324-120089, reverse complement, Verified ORF YDR232W 15.77 0.98 1 86.8758 1 YDR232W HEM1 SGDID:S000002640,5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p, Chr IV from 927448-929094, Verified ORF YDR483W 17.39 1.00 17 1366.6403 1 YDR483W KRE2 SGDID:S000002891,Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation, Chr IV from 1421149-1422477, Verified ORF YMR019W 27.91 1.00 10 500.8931 1 YMR019W STB4 SGDID:S000004621,Protein that binds Sin3p in a two-hybrid assay; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins, Chr XIII from 312155-315004, Verified ORF YKL007W 12.3 0.97 5 551.241 1 YKL007W CAP1 SGDID:S000001490,Alpha subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches, Chr XI from 428945-429751, Verified ORF YCR026C 22.31 0.88 4 220.5707 1 YCR026C NPP1 SGDID:S000000621,Nucleotide pyrophosphatase\phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp2p and Pho5p; activity and expression enhanced during conditions of phosphate starvation, Chr III from 166335-164107, reverse complement, Verified ORF YDL213C 9.93 0.94 7 926.3637 1 YDL213C NOP6 SGDID:S000002372,Protein with similarity to hydrophilins, which are involved in the adaptive response to hyperosmotic conditions; computational analysis of large-scale protein-protein interaction data suggests a possible role in rRNA processing, Chr IV from 77967-77290, reverse complement, Uncharacterized ORF YLR326W 6 0.74 1 172.4191 1 YLR326W YLR326W SGDID:S000004318,Hypothetical protein, Chr XII from 782174-782896, Uncharacterized ORF YMR080C 38.12 1.00 8 293.3877 1 YMR080C NAM7 SGDID:S000004685,ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediated mRNA decay and for efficient translation termination at nonsense codons; involved in telomere maintenance, Chr XIII from 429626-426711, reverse complement, Verified ORF YOR324C 27.1 1.00 5 257.9322 1 YOR324C FRT1 SGDID:S000005851,Tail-anchored endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcineurin, interacts with homolog Frt2p, promotes cell growth in conditions of high Na+, alkaline pH, and cell wall stress, Chr XV from 925037-923229, reverse complement, Verified ORF YBL082C 8.638 1.00 8 1294.7374 1 YBL082C ALG3 SGDID:S000000178,Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins, Chr II from 71124-69748, reverse complement, Verified ORF YDR032C 7.15 1.00 59 11535.884 1 YDR032C PST2 SGDID:S000002439,Protein of unknown function with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; GFP-fusion protein localizes to the cytoplasm in a punctate pattern, Chr IV from 504692-504096, reverse complement, Verified ORF YNL134C 14.05 1.00 10 995.0126 1 YNL134C YNL134C SGDID:S000005078,Uncharacterized ORF, Chr XIV from 373583-372453, reverse complement, Uncharacterized ORF YJL014W 25.899 1.00 21 1133.5513 1 YJL014W CCT3 SGDID:S000003551,Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo, Chr X from 407474-409078, Verified ORF YCR033W 49.09 0.82 6 140.1125 1 YCR033W SNT1 SGDID:S000000629,Subunit of the Set3C deacetylase complex; putative DNA-binding protein, Chr III from 186485-190165, Verified ORF YBL047C 45.008 1.00 29 900.7685 1 YBL047C EDE1 SGDID:S000000143,Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins, Chr II from 132043-127898, reverse complement, Verified ORF YPL012W 46.778 1.00 30 896.5706 1 YPL012W RRP12 SGDID:S000005933,Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; contains HEAT-repeats, Chr XVI from 529720-533406, Verified ORF YER045C 10.34 0.68 1 91.9376 1 YER045C ACA1 SGDID:S000000847,Basic leucine zipper (bZIP) transcription factor of the ATF\CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources, Chr V from 241500-240031, reverse complement, Verified ORF YKR001C 37.25 1.00 73 2739.6904 1 YKR001C VPS1 SGDID:S000001709,GTPase required for vacuolar protein sorting, functions in actin cytoskeleton organization via its interaction with Sla1p; required for late Golgi-retention of some proteins including Kex2p; involved in regulating peroxisome biogenesis, Chr XI from 442365-440251, reverse complement, Verified ORF YOR126C 11.79 0.98 1 116.2029 1 YOR126C IAH1 SGDID:S000005652,Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing, Chr XV from 560678-559962, reverse complement, Verified ORF YBR154C 7.32 1.00 5 954.913 1 YBR154C RPB5 SGDID:S000000358,RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation, Chr II from 549003-548356, reverse complement, Verified ORF YJL020C 44.278 1.00 19 599.8884 1 YJL020C BBC1 SGDID:S000003557,Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches, Chr X from 402327-398854, reverse complement, Verified ORF YJL047C 37.466 0.90 11 369.405 1 YJL047C RTT101 SGDID:S000003583,Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenotype suggests a role in anaphase progression; interacts with Mms22p and implicated in Mms22-dependent DNA repair; modified by the ubiquitin-like protein, Rub1p, Chr X from 352025-349497, reverse complement, Verified ORF YPL105C 29.31 0.98 1 46.7428 1 YPL105C YPL105C SGDID:S000006026,Hypothetical protein, Chr XVI from 355409-352860, reverse complement, Uncharacterized ORF YDL167C 22.93 0.99 4 241.4326 1 YDL167C NRP1 SGDID:S000002326,Protein of unknown function, rich in asparagine residues, Chr IV from 163155-160996, reverse complement, Verified ORF YEL063C 13.348 0.95 3 298.4926 1 YEL063C CAN1 SGDID:S000000789,Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance, Chr V from 33466-31694, reverse complement, Verified ORF YLR340W 12.6 1.00 385 42716.4444 1 YLR340W RPP0 SGDID:S000004332,Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphorylated on serine 302, Chr XII from 805887-806825, Verified ORF YOR131C 10.217 1.00 4 547.3202 1 YOR131C YOR131C SGDID:S000005657,Hypothetical protein, Chr XV from 572839-572183, reverse complement, Uncharacterized ORF YDR345C 11.08 1.00 34 4289.8693 1 YDR345C HXT3 SGDID:S000002753,Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions, Chr IV from 1164654-1162951, reverse complement, Verified ORF YGL008C 17.56 1.00 450 35825.5539 1 YGL008C PMA1 SGDID:S000002976,Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; part of the P2 subgroup of cation-transporting ATPases, Chr VII from 482671-479915, reverse complement, Verified ORF YOR108W 20.09 1.00 38 2644.2868 1 YOR108W LEU9 SGDID:S000005634,Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant, Chr XV from 523028-524842, Verified ORF YEL032W 50.449 0.95 1 26.3254 1 YEL032W MCM3 SGDID:S000000758,Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex, Chr V from 86937-89852, Verified ORF YLR212C 10.55 0.99 3 393.5581 1 YLR212C TUB4 SGDID:S000004202,Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body, Chr XII from 566283-564862, reverse complement, Verified ORF YBR222C 24.92 0.75 1 42.0744 1 YBR222C PCS60 SGDID:S000000426,Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase, Chr II from 668346-666715, reverse complement, Verified ORF YDL095W 22.15 1.00 27 1704.0994 1 YDL095W PMT1 SGDID:S000002253,Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine\threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals, Chr IV from 287059-289512, Verified ORF YBR015C 29.83 0.98 6 275.5681 1 YBR015C MNN2 SGDID:S000000219,Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment, Chr II from 269503-267710, reverse complement, Verified ORF YDR361C 15.428 1.00 11 996.7539 1 YDR361C BCP1 SGDID:S000002769,Essential protein involved in nuclear export of Mss4p, which is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport, Chr IV from 1196255-1195404, reverse complement, Uncharacterized ORF YOR323C 23.429 1.00 69 4117.1837 1 YOR323C PRO2 SGDID:S000005850,Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis, Chr XV from 922902-921532, reverse complement, Verified ORF YMR183C 7.8 0.99 6 1064.6252 1 YMR183C SSO2 SGDID:S000004795,Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p, Chr XIII from 627807-626920, reverse complement, Verified ORF YIL151C 37.756 0.80 2 59.2432 1 YIL151C YIL151C SGDID:S000001413,Hypothetical protein, Chr IX from 60694-57338, reverse complement, Uncharacterized ORF YPL009C 41.867 1.00 39 1302.2599 1 YPL009C YPL009C SGDID:S000005930,Hypothetical protein, Chr XVI from 538933-535817, reverse complement, Uncharacterized ORF YNL065W 15.67 0.90 5 401.4656 1 YNL065W AQR1 SGDID:S000005009,Plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine, Chr XIV from 503725-505485, Verified ORF YLR127C 36.058 0.98 9 341.9572 1 YLR127C APC2 SGDID:S000004117,Subunit of the Anaphase-Promoting Complex\Cyclosome (APC\C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase\anaphase transition; similar to cullin Cdc53p, Chr XII from 398320-395759, reverse complement, Verified ORF YPL063W 25.51 1.00 25 1370.0438 1 YPL063W TIM50 SGDID:S000005984,Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex); may promote binding of incoming precursor proteins to the intermembrane space domain of Tom22p during translocation, Chr XVI from 429936-431366, Verified ORF YJL222W 57.49 1.00 7 170.22 2 YJL222W,YIL173W VTH2 SGDID:S000003758,Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p\Vps10p, may be involved in vacuolar protein sorting, Chr X from 11475-16124, Verified ORF YHL038C 24.218 0.88 10 507.9831 1 YHL038C CBP2 SGDID:S000001030,Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene, Chr VIII from 25506-23614, reverse complement, Verified ORF YDR457W 135.215 0.99 5 51.1782 1 YDR457W TOM1 SGDID:S000002865,E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators, Chr IV from 1369782-1379588, Verified ORF YFR024C-A 21.07 1.00 9 597.1492 1 YFR024C-A LSB3 SGDID:S000002968,Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization, Chr VI from 203421-203375,203256-201948, reverse complement, Verified ORF YOL111C 12.578 1.00 17 1889.4797 1 YOL111C MDY2 SGDID:S000005471,Nuclear protein required for efficient mating, involved in shmoo formation and nuclear migration in the pre-zygote, contains a ubiquitin-like (UBL) domain, Chr XV from 108896-108258, reverse complement, Verified ORF YER009W 3.97 1.00 35 12324.8729 1 YER009W NTF2 SGDID:S000000811,Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport, Chr V from 172114-172491, Verified ORF YPR110C 17.34 1.00 23 1854.3156 1 YPR110C RPC40 SGDID:S000006314,RNA polymerase subunit, common to RNA polymerase I and III, Chr XVI from 746833-745826, reverse complement, Verified ORF YOR154W 21.99 0.88 3 167.8354 1 YOR154W YOR154W SGDID:S000005680,Hypothetical protein, Chr XV from 624730-626493, Uncharacterized ORF YMR219W 66.889 1.00 18 376.2033 1 YMR219W ESC1 SGDID:S000004832,Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p, Chr XIII from 707132-712108, Verified ORF YNL324W 2.77 0.74 1 373.4709 1 YNL324W YNL324W SGDID:S000005268,Hypothetical protein, Chr XIV from 31049-31444, Dubious ORF YMR238W 8.579 1.00 2 325.9104 1 YMR238W DFG5 SGDID:S000004851,Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p, Chr XIII from 746352-747728, Verified ORF YFL034C-B 12.14 0.86 3 297.1022 1 YFL034C-B MOB2 SGDID:S000001859,Component of the RAM signaling network, localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation; Mob1p-like protein, Chr VI from 63992-63973,63858-63015, reverse complement, Verified ORF YNR016C 92.1000000000001 1.00 265 4022.4546 1 YNR016C ACC1 SGDID:S000005299,Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids, Chr XIV from 661376-654675, reverse complement, Verified ORF YER123W 18.42 0.85 1 64.511 1 YER123W YCK3 SGDID:S000000925,Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of the HOPS complex subunit, Vps41p; shares overlapping essential functions with Hrr25p, Chr V from 404809-406383, Verified ORF YBL032W 14.72 0.98 6 558.4373 1 YBL032W HEK2 SGDID:S000000128,RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length, Chr II from 160187-161332, Verified ORF YKR054C 184.486 1.00 13 98.511 1 YKR054C DYN1 SGDID:S000001762,Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p, Chr XI from 547567-535289, reverse complement, Verified ORF YGL105W 16.837 1.00 62 5147.9211 1 YGL105W ARC1 SGDID:S000003073,Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids, Chr VII from 307440-308570, Verified ORF YMR315W 16.85 1.00 21 1742.3054 1 YMR315W YMR315W SGDID:S000004932,Hypothetical protein, Chr XIII from 902799-903848, Uncharacterized ORF YDR388W 13.92 1.00 19 1908.1797 1 YDR388W RVS167 SGDID:S000002796,Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in regulation of actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin, Chr IV from 1250178-1251626, Verified ORF YAL024C 71.118 0.96 5 94.3553 1 YAL024C LTE1 SGDID:S000000022,Putative GDP\GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP, Chr I from 105873-101566, reverse complement, Verified ORF YLR215C 19.03 0.92 2 135.1711 1 YLR215C CDC123 SGDID:S000004205,Protein involved in nutritional control of the cell cycle; regulates abundance of the translation initiation factor eIF2; ortholog of human D123 protein, Chr XII from 571860-570778, reverse complement, Verified ORF YGR090W 55.017 1.00 18 457.3835 1 YGR090W UTP22 SGDID:S000003322,Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data, Chr VII from 662362-666075, Uncharacterized ORF YOR375C 18.87 1.00 245 18150.9389 1 YOR375C GDH1 SGDID:S000005902,NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources, Chr XV from 1043040-1041676, reverse complement, Verified ORF YHR066W 13.98 0.99 1 98.9994 1 YHR066W SSF1 SGDID:S000001108,Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family, Chr VIII from 229337-230698, Verified ORF YBL022C 61.736 1.00 10 226.4469 1 YBL022C PIM1 SGDID:S000000118,Mitochondrial ATP-dependent protease involved in intramitochondrial proteolysis; involved in degradation of misfolded proteins in mitochondria; required for bigenesis and maintenance of mitochondria, Chr II from 181278-177877, reverse complement, Verified ORF YKL216W 7.78 1.00 42 7547.0044 1 YKL216W URA1 SGDID:S000001699,Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid, Chr XI from 25216-26160, Verified ORF YDR162C 7.31 0.99 6 1135.9886 1 YDR162C NBP2 SGDID:S000002569,Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p, Chr IV from 781097-780387, reverse complement, Verified ORF YHR088W 16.74 1.00 8 668.0968 1 YHR088W RPF1 SGDID:S000001130,Nucleolar protein involved in the assembly of the large ribosomal subunit; constituent of 66S pre-ribosomal particles; contains a sigma(70)-like motif, which is thought to bind RNA, Chr VIII from 281497-282384, Verified ORF YDL171C 91.265 1.00 104 1593.0668 1 YDL171C GLT1 SGDID:S000002330,NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source, Chr IV from 155641-149204, reverse complement, Verified ORF YPR052C 5.97 1.00 22 5151.7319 1 YPR052C NHP6A SGDID:S000006256,High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Bp; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters, Chr XVI from 665971-665690, reverse complement, Verified ORF YDR035W 13.65 1.00 8 819.3363 1 YDR035W ARO3 SGDID:S000002442,3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine, Chr IV from 521813-522925, Verified ORF YBL063W 43.7 0.81 4 103.6498 1 YBL063W KIP1 SGDID:S000000159,Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p , Chr II from 101888-105223, Verified ORF YML094W 10.01 1.00 12 1675.9153 1 YML094W GIM5 SGDID:S000004559,Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it, Chr XIII from 82275-82290,82374-82849, Verified ORF YMR045C 60.12 0.68 1 15.8122 2 YBL005W-B,YMR045C YMR045C SGDID:S000004648,TyB Gag-Pol protein; proteolytically processed to make the Gag, RT, PR, and IN proteins that are required for retrotransposition, Chr XIII from 362626-361322,361320-357358, reverse complement, transposable_element_gene YMR049C 34.345 1.00 38 1546.7673 1 YMR049C ERB1 SGDID:S000004652,Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1, Chr XIII from 370516-368093, reverse complement, Verified ORF YER151C 36.19 1.00 11 424.9218 1 YER151C UBP3 SGDID:S000000953,Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin, Chr V from 472419-469681, reverse complement, Verified ORF YCL039W 22.89 0.72 3 131.9206 1 YCL039W GID7 SGDID:S000000544,Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions, Chr III from 52645-54882, Verified ORF YHR207C 24.268 0.82 6 283.4236 1 YHR207C SET5 SGDID:S000001250,Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus, Chr VIII from 516485-514905, reverse complement, Verified ORF YDR171W 11.6 1.00 3 361.5498 1 YDR171W HSP42 SGDID:S000002578,Small cytosolic stress-induced chaperone that forms barrel-shaped oligomers and suppresses the aggregation of non-native proteins; oligomer dissociation is not required for function; involved in cytoskeleton reorganization after heat shock, Chr IV from 806618-807745, Verified ORF YNL126W 32.42 0.80 2 68.994 1 YNL126W SPC98 SGDID:S000005070,Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque, Chr XIV from 387229-389769, Verified ORF YPR019W 42.94 0.92 3 89.857 1 YPR019W CDC54 SGDID:S000006223,Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p, Chr XVI from 596747-599548, Verified ORF YPR190C 29.64 0.98 1 46.2224 1 YPR190C RPC82 SGDID:S000006394,RNA polymerase III subunit C82, Chr XVI from 919037-917073, reverse complement, Verified ORF YNR017W 6.05 0.99 2 457.5248 1 YNR017W MAS6 SGDID:S000005300,Essential protein of the mitochondrial inner membrane, component of the mitochondrial import system, Chr XIV from 662915-663583, Verified ORF YOR258W 9.93 0.89 1 125.2984 1 YOR258W HNT3 SGDID:S000005784,Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia, Chr XV from 811671-812324, Verified ORF YDR353W 11.8 1.00 135 15993.9846 1 YDR353W TRR1 SGDID:S000002761,Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress, Chr IV from 1183292-1184251, Verified ORF YNL023C 35.5 1.00 8 315.0406 1 YNL023C FAP1 SGDID:S000004968,Protein that binds to Fpr1p (FKBP12), conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; has similarity to putative transcription factors, including D. melanogaster shuttle craft and human NFX1, Chr XIV from 591161-588264, reverse complement, Verified ORF YIL015W 11.78 1.00 5 593.3755 1 YIL015W BAR1 SGDID:S000001277,Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest, Chr IX from 322340-324103, Verified ORF YNL052W 7.82 1.00 4 715.0857 1 YNL052W COX5A SGDID:S000004997,Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth, Chr XIV from 531726-532187, Verified ORF YJL206C 28.8 0.78 3 113.5869 1 YJL206C YJL206C SGDID:S000003741,Putative protein of unknown function; similar to transcriptional regulators from the Zn[2]-Cys[6] binuclear cluster protein family; mRNA is weakly cell cycle regulated, peaking in S phase; induced rapidly upon MMS treatment, Chr X from 49935-47659, reverse complement, Uncharacterized ORF YKL192C 5.51 0.99 2 502.3639 1 YKL192C ACP1 SGDID:S000001675,Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p, Chr XI from 80542-80165, reverse complement, Verified ORF YFL018C 27.677 1.00 28 1414.3077 1 YFL018C LPD1 SGDID:S000001876,Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes, Chr VI from 103121-101622, reverse complement, Verified ORF YNL050C 9.18 0.77 17 1993.434 1 YNL050C YNL050C SGDID:S000004995,Hypothetical protein, Chr XIV from 534983-534967,534875-534080, reverse complement, Uncharacterized ORF YGL055W 18.77 1.00 23 1713.0438 1 YGL055W OLE1 SGDID:S000003023,Fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria, Chr VII from 398631-400163, Verified ORF YHR111W 14 1.00 4 399.4264 1 YHR111W UBA4 SGDID:S000001153,Protein that activates Urm1p before its conjugation to proteins (urmylation); one target is the thioredoxin peroxidase Ahp1p, suggesting a role of urmylation in the oxidative stress response, Chr VIII from 333075-334397, Verified ORF YNL096C 11.27 1.00 115 14265.2319 1 YNL096C RPS7B SGDID:S000005040,Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Ap; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins, Chr XIV from 444317-444174,443828-443400, reverse complement, Verified ORF YLL034C 36.754 0.99 3 112.9683 1 YLL034C RIX7 SGDID:S000003957,Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions, Chr XII from 73145-70632, reverse complement, Verified ORF YHR019C 25.128 1.00 196 10904.4323 1 YHR019C DED81 SGDID:S000001061,Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA, Chr VIII from 143551-141887, reverse complement, Verified ORF YHR013C 14.32 1.00 8 781.0015 1 YHR013C ARD1 SGDID:S000001055,Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing, Chr VIII from 131440-130724, reverse complement, Verified ORF YKL214C 11.03 0.99 2 250.9542 1 YKL214C YRA2 SGDID:S000001697,Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus, Chr XI from 31694-31083, reverse complement, Verified ORF YNL073W 29.92 0.99 24 1110.1706 1 YNL073W MSK1 SGDID:S000005017,Mitochondrial lysine-tRNA synthetase, required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria, Chr XIV from 488387-490117, Verified ORF YPL119C 31.88 0.90 4 157.8661 1 YPL119C DBP1 SGDID:S000006040,Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs, Chr XVI from 326263-324410, reverse complement, Verified ORF YLR075W 9.259 1.00 159 24007.0033 1 YLR075W RPL10 SGDID:S000004065,Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family, Chr XII from 282928-283593, Verified ORF YDL125C 10.448 1.00 40 5352.1926 1 YDL125C HNT1 SGDID:S000002283,Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint, Chr IV from 239606-239510,239398-239019, reverse complement, Verified ORF YHR186C 62.5 1.00 18 402.6219 1 YHR186C KOG1 SGDID:S000001229,Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors, Chr VIII from 480672-475999, reverse complement, Verified ORF YDR339C 5.25 0.75 3 599.1397 1 YDR339C YDR339C SGDID:S000002747,Nucleolar protein involved in pre-mRNA processing, Chr IV from 1150514-1149945, reverse complement, Uncharacterized ORF YNL144C 18.58 0.69 2 103.8336 1 YNL144C YNL144C SGDID:S000005088,Hypothetical protein, Chr XIV from 355044-352822, reverse complement, Uncharacterized ORF YLR435W 6.3 0.90 1 199.7132 1 YLR435W TSR2 SGDID:S000004427,Protein with a potential role in pre-rRNA processing, Chr XII from 1006375-1006992, Verified ORF YKL033W-A 10.69 1.00 7 915.4302 1 YKL033W-A YKL033W-A SGDID:S000007242,Putative protein of unknown function; similar to uncharacterized proteins from other fungi, Chr XI from 374148-374858, Uncharacterized ORF YJR092W 62.906 1.00 18 400.0233 1 YJR092W BUD4 SGDID:S000003852,Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate, Chr X from 598650-602996, Verified ORF YJL026W 17.079 1.00 39 3192.3248 1 YJL026W RNR2 SGDID:S000003563,Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits, Chr X from 392321-393520, Verified ORF YFR031C-A 8.06 1.00 133 23068.6145 2 YFR031C-A,YIL018W RPL2A SGDID:S000002104,Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins, Chr VI from 221406-221403,221255-220495, reverse complement, Verified ORF YDR012W 10.56 1.00 513 67913.8513 1 YDR012W RPL4B SGDID:S000002419,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Ap and has similarity to E. coli L4 and rat L4 ribosomal proteins, Chr IV from 471850-472938, Verified ORF YJR063W 3.35 1.00 15 6259.6689 1 YJR063W RPA12 SGDID:S000003824,RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex, Chr X from 555110-555487, Verified ORF YOR278W 13.44 0.76 1 79.0531 1 YOR278W HEM4 SGDID:S000005804,Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in the heme biosynthetic pathway, Chr XV from 842816-843643, Verified ORF YGR208W 13.86 0.98 4 395.3918 1 YGR208W SER2 SGDID:S000003440,Phosphoserine phosphatase of the phosphoglycerate pathway, involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source, Chr VII from 911888-912817, Verified ORF YLR078C 11.525 0.96 3 349.3465 1 YLR078C BOS1 SGDID:S000004068,v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi, Chr XII from 286560-286558,286468-285737, reverse complement, Verified ORF YIR003W 36.36 0.81 4 124.5736 1 YIR003W YIR003W SGDID:S000001442,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein colocalizes with Sac1p to the actin cytoskeleton; interacts with the SH3 domain of the actin binding protein Abp1p; YIR003W is a non-essential gene, Chr IX from 360882-362921, Uncharacterized ORF YDR201W 11.11 0.93 2 234.0473 1 YDR201W SPC19 SGDID:S000002609,Essential subunit of the DASH microtubule ring complex, couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body, Chr IV from 856314-856811, Verified ORF YIL053W 17.837 1.00 269 21083.1442 1 YIL053W RHR2 SGDID:S000001315,Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p\Gpp2p isoform, osmotic stress, Chr IX from 255113-255865, Verified ORF YPL028W 18.59 1.00 137 10302.5822 1 YPL028W ERG10 SGDID:S000005949,Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis, Chr XVI from 498094-499290, Verified ORF YLR214W 25.15 0.95 1 52.8068 1 YLR214W FRE1 SGDID:S000004204,Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low copper and iron levels, Chr XII from 568569-570629, Verified ORF YDR258C 42 1.00 6 199.7132 1 YDR258C HSP78 SGDID:S000002666,Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; prevents the aggregation of misfolded matrix proteins; component of the mitochondrial proteolysis system, Chr IV from 974239-971804, reverse complement, Verified ORF YLR027C 18.45 1.00 91 6895.2486 1 YLR027C AAT2 SGDID:S000004017,Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells, Chr XII from 198086-196830, reverse complement, Verified ORF YBR198C 36.263 1.00 9 346.9634 1 YBR198C TAF5 SGDID:S000000402,Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, Chr II from 618518-616122, reverse complement, Verified ORF YOR275C 30.91 0.83 3 112.6173 1 YOR275C RIM20 SGDID:S000005801,Protein involved in proteolytic activation of Rim101p in response to alkaline pH; member of the PalA\AIP1\Alix family; interacts with the ESCRT-III subunits Snf7p, suggesting a relationship between the response to pH and multivesicular body formation, Chr XV from 841068-839083, reverse complement, Verified ORF YGL245W 34.628 1.00 221 8922.1552 1 YGL245W GUS1 SGDID:S000003214,Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm, Chr VII from 39023-41149, Verified ORF YNL243W 33.66 1.00 13 539.9258 1 YNL243W SLA2 SGDID:S000005187,Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo, Chr XIV from 188052-190958, Verified ORF YPL209C 14 0.69 2 137.8021 1 YPL209C IPL1 SGDID:S000006130,Aurora kinase involved in regulating kinetochore-microtubule attachments, associates with Sli15p, which stimulates Ipl1p kinase activity and promotes its association with the mitotic spindle, potential Cdc28p substrate, Chr XVI from 157592-156489, reverse complement, Verified ORF YPR181C 25.76 1.00 67 3636.0835 1 YPR181C SEC23 SGDID:S000006385,GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p, Chr XVI from 899663-897357, reverse complement, Verified ORF YCR084C 28.45 1.00 23 1130.1874 1 YCR084C TUP1 SGDID:S000000680,General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes, Chr III from 262449-260308, reverse complement, Verified ORF YKR060W 16.237 0.75 1 64.5744 1 YKR060W UTP30 SGDID:S000001768,Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data, Chr XI from 556160-556984, Uncharacterized ORF YKL210W 43.316 1.00 188 6067.5647 1 YKL210W UBA1 SGDID:S000001693,Ubiquitin activating enzyme, involved in ubiquitin-mediated protein degradation and essential for viability, Chr XI from 39164-42238, Verified ORF YDR508C 18.689 1.00 8 598.4237 1 YDR508C GNP1 SGDID:S000002916,High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids, Chr IV from 1468436-1466445, reverse complement, Verified ORF YBR106W 8.83 1.00 66 10449.3227 1 YBR106W PHO88 SGDID:S000000310,Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations, Chr II from 452652-453218, Verified ORF YHR018C 21.32 1.00 18 1180.294 1 YHR018C ARG4 SGDID:S000001060,Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway, Chr VIII from 141395-140004, reverse complement, Verified ORF YLR318W 38.71 0.83 28 839.3012 1 YLR318W EST2 SGDID:S000004310,Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia, Chr XII from 766542-769196, Verified ORF YBR179C 33.906 1.00 9 371.0828 1 YBR179C FZO1 SGDID:S000000383,Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome; contains N-terminal GTPase domain, Chr II from 589109-586542, reverse complement, Verified ORF YFL009W 31.46 0.96 7 298.6176 1 YFL009W CDC4 SGDID:S000001885,F-box protein required for G1\S and G2\M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p, Chr VI from 116139-118478, Verified ORF YKL195W 22.15 1.00 18 1136.0663 1 YKL195W MIA40 SGDID:S000001678,Essential protein of the mitochondrial intermembrane space, involved in import and assembly of intermembrane space proteins, Chr XI from 75826-77037, Verified ORF YMR039C 16.56 1.00 15 1266.2977 1 YMR039C SUB1 SGDID:S000004642,Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations, Chr XIII from 349521-348643, reverse complement, Verified ORF YPL188W 9.13 0.97 3 445.5814 1 YPL188W POS5 SGDID:S000006109,Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress, Chr XVI from 191405-192649, Verified ORF YGL147C 8.47 1.00 201 33175.5063 1 YGL147C RPL9A SGDID:S000003115,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins, Chr VII from 228334-227759, reverse complement, Verified ORF YLR257W 15.16 0.99 3 273.8811 1 YLR257W YLR257W SGDID:S000004247,Hypothetical protein, Chr XII from 658828-659793, Uncharacterized ORF YPL078C 11.749 1.00 16 1903.8116 1 YPL078C ATP4 SGDID:S000005999,Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis, Chr XVI from 408741-408007, reverse complement, Verified ORF YJR126C 33.808 0.97 5 200.552 1 YJR126C VPS70 SGDID:S000003887,Protein of unknown function involved in vacuolar protein sorting, Chr X from 658605-656170, reverse complement, Verified ORF YIL074C 20.04 1.00 16 1116.1618 1 YIL074C SER33 SGDID:S000001336,3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p, Chr IX from 222487-221078, reverse complement, Verified ORF YGR031W 15.19 0.66 1 60.7422 1 YGR031W YGR031W SGDID:S000003263,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion, Chr VII from 546445-547473, Uncharacterized ORF YDL145C 48.8 1.00 128 3666.8661 1 YDL145C COP1 SGDID:S000002304,Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway, Chr IV from 198177-194572, reverse complement, Verified ORF YOR033C 27.731 0.98 12 592.8525 1 YOR033C EXO1 SGDID:S000005559,5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains, Chr XV from 394524-392416, reverse complement, Verified ORF YJL041W 24.66 1.00 20 1133.814 1 YJL041W NSP1 SGDID:S000003577,Essential component of the nuclear pore complex, which mediates nuclear import and export, Chr X from 365701-365701,365820-368290, Verified ORF YPR088C 24.82 1.00 9 506.9272 1 YPR088C SRP54 SGDID:S000006292,Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain, Chr XVI from 713026-711401, reverse complement, Verified ORF YHR073W 45.54 0.86 6 158.4023 1 YHR073W OSH3 SGDID:S000001115,Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability, Chr VIII from 242584-245574, Verified ORF YPR063C 3.13 0.98 3 1313.1305 1 YPR063C YPR063C SGDID:S000006267,Hypothetical protein, Chr XVI from 678317-678277,678190-677809, reverse complement, Uncharacterized ORF YGR200C 34.26 1.00 6 244.8323 1 YGR200C ELP2 SGDID:S000003432,Elongator protein, part of the six-subunit RNA polymerase II Elongator histone acetyltransferase complex; target of Kluyveromyces lactis zymocin, Chr VII from 902275-899909, reverse complement, Verified ORF YOL007C 6.56 0.78 2 332.4494 1 YOL007C YOL007C SGDID:S000005367,Appears to be a structural component of the chitin synthase 3 complex, Chr XV from 312368-311343, reverse complement, Uncharacterized ORF YDR399W 10.26 1.00 42 5722.7772 1 YDR399W HPT1 SGDID:S000002807,Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome, Chr IV from 1270060-1270725, Verified ORF YOR197W 10.2 1.00 14 1918.8135 1 YOR197W MCA1 SGDID:S000005723,Putative cysteine protease similar to mammalian caspases, involved in regulation of apoptosis upon hydrogen peroxide treatment, Chr XV from 717024-718385, Verified ORF YDL185W 47.97 1.00 276 8043.4853 1 YDL185W TFP1 SGDID:S000002344,Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease, Chr IV from 126788-130003, Verified ORF YER107C 9.55 0.99 5 724.614 1 YER107C GLE2 SGDID:S000000909,Component of the nuclear pore complex required for polyadenylated RNA export but not for protein import, homologous to S. pombe Rae1p, Chr V from 374541-373444, reverse complement, Verified ORF YKL024C 11.54 1.00 7 848.0025 1 YKL024C URA6 SGDID:S000001507,Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP), Chr XI from 392783-392169, reverse complement, Verified ORF YKL181W 14.65 0.94 3 269.1016 1 YKL181W PRS1 SGDID:S000001664,5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes, Chr XI from 107321-108604, Verified ORF YGL038C 17.35 0.66 1 53.1801 1 YGL038C OCH1 SGDID:S000003006,Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins, Chr VII from 426810-425368, reverse complement, Verified ORF YMR075W 38.34 0.94 7 239.9267 1 YMR075W YMR075W SGDID:S000004680,Nuclear protein of unknown function, Chr XIII from 413981-416035, Uncharacterized ORF YMR012W 55.229 1.00 89 2252.8264 1 YMR012W CLU1 SGDID:S000004614,eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant, Chr XIII from 291133-294966, Verified ORF YDR049W 29.24 0.91 1 43.5079 1 YDR049W YDR049W SGDID:S000002456,Hypothetical protein, Chr IV from 553252-555150, Uncharacterized ORF YGR192C 15.07 1.00 1229 114010.1568 1 YGR192C TDH3 SGDID:S000003424,Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall , Chr VII from 883815-882817, reverse complement, Verified ORF YDL078C 19.29 1.00 33 2391.5894 1 YDL078C MDH3 SGDID:S000002236,Cytoplasmic malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle, Chr IV from 316388-315357, reverse complement, Verified ORF YHR200W 8.01 1.00 5 872.6546 1 YHR200W RPN10 SGDID:S000001243,Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein, Chr VIII from 499079-499885, Verified ORF YMR226C 13.02 1.00 40 4294.9085 1 YMR226C YMR226C SGDID:S000004839,NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids, Chr XIII from 722395-721592, reverse complement, Uncharacterized ORF YOL041C 25.23 1.00 20 1108.1987 1 YOL041C NOP12 SGDID:S000005401,Nucleolar protein, required for pre-25S rRNA processing; contains an RNA recognition motif (RRM) and has similarity to Nop13p, Nsr1p, and putative orthologs in Drosophila and S. pombe, Chr XV from 252645-251266, reverse complement, Verified ORF YJL043W 8.5 0.90 1 148.0227 1 YJL043W YJL043W SGDID:S000003579,Putative protein of unknown function; YJL043W is a non-essential gene, Chr X from 360047-360820, Uncharacterized ORF YJL052W 16.249 1.00 232 19960.2629 1 YJL052W TDH1 SGDID:S000003588,Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall , Chr X from 338188-339186, Verified ORF YHR023W 104.625 0.80 4 42.7582 1 YHR023W MYO1 SGDID:S000001065,Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively, Chr VIII from 151659-157445, Verified ORF YHR079C 50.54 1.00 11 304.2722 1 YHR079C IRE1 SGDID:S000001121,Serine-threonine kinase and endoribonuclease; transmembrane protein that initiates the unfolded protein response signal by regulating synthesis of Hac1p through HAC1 mRNA splicing, Chr VIII from 261593-258246, reverse complement, Verified ORF YLR006C 24.86 1.00 14 787.2847 1 YLR006C SSK1 SGDID:S000003996,Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate, Chr XII from 163892-161754, reverse complement, Verified ORF YKL008C 11.8 0.78 3 277.229 1 YKL008C LAC1 SGDID:S000001491,Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p, Chr XI from 428194-426938, reverse complement, Verified ORF YEL030W 31.07 1.00 64 2879.676 1 YEL030W ECM10 SGDID:S000000756,Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protein translocation, interacts with Mge1p in an ATP-dependent manner; overexpression induces extensive mitochondrial DNA aggregations, Chr V from 94644-96578, Verified ORF YIR034C 14.12 1.00 11 1089.0878 1 YIR034C LYS1 SGDID:S000001473,Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway, Chr IX from 420733-419612, reverse complement, Verified ORF YMR291W 20.08 1.00 15 1044.3172 1 YMR291W YMR291W SGDID:S000004905,Hypothetical protein, Chr XIII from 852629-854389, Uncharacterized ORF YPL048W 17.53 1.00 108 8612.8473 1 YPL048W CAM1 SGDID:S000005969,Translational cofactor elongation factor-1 gamma, participates in the regulation of GTP-binding protein EF-1 alpha, may play a redundant role in the regulation of protein synthesis or another GTP-dependent process, Chr XVI from 464398-465645, Verified ORF YLR451W 31.907 0.97 4 170.0006 1 YLR451W LEU3 SGDID:S000004443,Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis, Chr XII from 1036090-1038750, Verified ORF YLR178C 8.31 1.00 4 672.9206 1 YLR178C TFS1 SGDID:S000004168,Carboxypeptidase Y inhibitor, function requires acetylation by the NatB N-terminal acetyltransferase; phosphatidylethanolamine-binding protein involved in protein kinase A signaling pathway, Chr XII from 513823-513164, reverse complement, Verified ORF YML063W 13.8 1.00 424 42952.82 1 YML063W RPS1B SGDID:S000004528,Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein, Chr XIII from 146482-147249, Verified ORF YEL046C 14.908 1.00 58 5438.9306 1 YEL046C GLY1 SGDID:S000000772,Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis, Chr V from 68792-67629, reverse complement, Verified ORF YGL120C 29.25 1.00 48 2294.1419 1 YGL120C PRP43 SGDID:S000003088,RNA helicase in the DEAH-box family, involved in release of the lariat-intron from the spliceosome, Chr VII from 283943-281640, reverse complement, Verified ORF YGR136W 6.28 1.00 13 2893.9339 1 YGR136W LSB1 SGDID:S000003368,Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization, Chr VII from 762433-763158, Verified ORF YMR242C 8.86 1.00 158 24930.3443 2 YOR312C,YMR242C RPL20A SGDID:S000004855,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Bp and has similarity to rat L18a ribosomal protein, Chr XIII from 754196-754178,753741-753224, reverse complement, Verified ORF YDR372C 15.729 0.99 2 175.9823 1 YDR372C VPS74 SGDID:S000002780,Non-essential protein of unknown function involved in vacuolar protein sorting; belongs to a family of cytosolic Golgi-associated proteins suggesting that it may play a role in secretion; also detected in the nucleus, Chr IV from 1222141-1221104, reverse complement, Verified ORF YOR184W 19.898 1.00 79 5550.3782 1 YOR184W SER1 SGDID:S000005710,3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p, Chr XV from 679358-680545, Verified ORF YER136W 19.977 1.00 37 2589.2642 1 YER136W GDI1 SGDID:S000000938,GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4\Ypt\rab family of GTP binding proteins, Chr V from 439612-440967, Verified ORF YGL116W 23.01 0.80 10 486.047 1 YGL116W CDC20 SGDID:S000003084,Cell-cycle regulated activator of anaphase-promoting complex\cyclosome (APC\C), which is required for metaphase\anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate, Chr VII from 289812-291644, Verified ORF YMR203W 10.52 1.00 39 5182.6726 1 YMR203W TOM40 SGDID:S000004816,Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore, Chr XIII from 668491-669654, Verified ORF YLR197W 22.68 1.00 220 13560.776 1 YLR197W SIK1 SGDID:S000004187,Essential evolutionarily-conserved nucleolar protein component of the box C\D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects, Chr XII from 546099-547613, Verified ORF YMR145C 27.3 1.00 8 409.6681 1 YMR145C NDE1 SGDID:S000004753,Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain, Chr XIII from 556474-554792, reverse complement, Verified ORF YLL031C 19.108 0.89 2 130.2295 1 YLL031C GPI13 SGDID:S000003954,ER membrane localized phosphoryltransferase that adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein, Chr XII from 80204-77151, reverse complement, Verified ORF YDR300C 22.368 1.00 14 874.9954 1 YDR300C PRO1 SGDID:S000002708,Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis, Chr IV from 1062787-1061501, reverse complement, Verified ORF YIR008C 20.32 0.99 1 68.1108 1 YIR008C PRI1 SGDID:S000001447,Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair, Chr IX from 374303-373074, reverse complement, Verified ORF YJR047C 9.217 0.95 3 432.275 1 YJR047C ANB1 SGDID:S000003808,Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions, Chr X from 525296-524823, reverse complement, Verified ORF YLR229C 4.467 0.98 2 613.4017 1 YLR229C CDC42 SGDID:S000004219,Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins, Chr XII from 604789-604214, reverse complement, Verified ORF YBL024W 37.15 1.00 26 978.4067 1 YBL024W NCL1 SGDID:S000000120,S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120, Chr II from 172537-174591, Verified ORF YLR406C 6.13 1.00 108 24630.2144 2 YLR406C,YDL075W RPL31B SGDID:S000004398,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p, Chr XII from 931754-931698,931348-931064, reverse complement, Verified ORF YJL082W 37.19 0.85 4 127.8078 1 YJL082W IML2 SGDID:S000003618,Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus, Chr X from 281102-283297, Verified ORF YLR392C 24.33 1.00 16 919.354 1 YLR392C YLR392C SGDID:S000004384,Hypothetical protein, Chr XII from 906305-904749, reverse complement, Uncharacterized ORF YGR075C 10.28 0.67 1 91.1143 1 YGR075C PRP38 SGDID:S000003307,Unique component of the U4\U6.U5 tri-snRNP particle, dispensable for spliceosome assembly, but required for conformational changes which lead to catalytic activation of the spliceosome, Chr VII from 636879-636151, reverse complement, Verified ORF YLR351C 15.246 1.00 6 550.1742 1 YLR351C NIT3 SGDID:S000004343,Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member, Chr XII from 830363-829488, reverse complement, Verified ORF YOR340C 13.55 1.00 13 1341.2476 1 YOR340C RPA43 SGDID:S000005867,RNA polymerase I subunit A43, Chr XV from 960179-959199, reverse complement, Verified ORF YDL198C 17.02 1.00 8 657.1058 1 YDL198C GGC1 SGDID:S000002357,Mitochondrial GTP\GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family; (putative) mitochondrial carrier protein, Chr IV from 104552-103650, reverse complement, Verified ORF YAL026C 48.158 0.99 1 28.739 1 YAL026C DRS2 SGDID:S000000024,Integral membrane Ca(2+)-ATPase involved in aminophospholipid translocation; required to form a specific class of secretory vesicles that accumulate upon actin cytoskeleton disruption; mutation affects maturation of the 18S rRNA, Chr I from 99698-95631, reverse complement, Verified ORF YLR001C 17.619 0.66 2 104.7363 1 YLR001C YLR001C SGDID:S000003991,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; also found in mitochondria; YLR001C is not an essential gene, Chr XII from 153976-151388, reverse complement, Uncharacterized ORF YDR316W 22.827 0.75 23 1056.4408 1 YDR316W OMS1 SGDID:S000002724,Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations, Chr IV from 1093760-1095175, Verified ORF YAL003W 7.84 1.00 334 59557.3432 1 YAL003W EFB1 SGDID:S000000003,Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site, Chr I from 142176-142255,142622-143162, Verified ORF YBL008W 36.717 0.99 10 376.9406 1 YBL008W HIR1 SGDID:S000000104,Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3 and H4 genes; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores, Chr II from 209656-212178, Verified ORF YPR033C 28.76 1.00 85 4131.7587 1 YPR033C HTS1 SGDID:S000006237,Cytoplasmic and mitochondrial histidine tRNA synthetase; encoded by a single nuclear gene that specifies two messages; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence , Chr XVI from 639016-637376, reverse complement, Verified ORF YML130C 26.12 0.99 5 264.9335 1 YML130C ERO1 SGDID:S000004599,Glycoprotein required for oxidative protein folding in the endoplasmic reticulum, Chr XIII from 13175-11484, reverse complement, Verified ORF YPL049C 14.04 0.99 6 591.4584 1 YPL049C DIG1 SGDID:S000005970,Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription, Chr XVI from 463836-462478, reverse complement, Verified ORF YJL117W 12.2 1.00 21 2406.3809 1 YJL117W PHO86 SGDID:S000003653,Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles, Chr X from 192452-193387, Verified ORF YMR162C 59.356 1.00 21 494.6062 1 YMR162C DNF3 SGDID:S000004772,Non-essential P-type ATPase involved in aminophospholipid translocation, localizes to the trans-Golgi, likely involved in protein transport, Chr XIII from 583920-578950, reverse complement, Verified ORF YHR068W 17.38 1.00 45 3619.6589 1 YHR068W DYS1 SGDID:S000001110,Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric, Chr VIII from 232135-233298, Verified ORF YDR019C 14.31 1.00 5 488.467 1 YDR019C GCV1 SGDID:S000002426,T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm, Chr IV from 485362-484160, reverse complement, Verified ORF YNL084C 18.74 0.99 4 295.4136 1 YNL084C END3 SGDID:S000005028,EH domain-containing protein involved in endocytosis, actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p, Chr XIV from 471104-470055, reverse complement, Verified ORF YDR430C 56.25 0.89 3 66.358 1 YDR430C CYM1 SGDID:S000002838,Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology, Chr IV from 1328462-1325493, reverse complement, Verified ORF YDR050C 15.44 1.00 345 31237.5318 1 YDR050C TPI1 SGDID:S000002457,Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region, Chr IV from 556470-555724, reverse complement, Verified ORF YPR160W 39.865 0.99 4 138.8699 1 YPR160W GPH1 SGDID:S000006364,Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway, Chr XVI from 861302-864010, Verified ORF YOR117W 25.9 1.00 28 1511.3434 1 YOR117W RPT5 SGDID:S000005643,One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription, Chr XV from 545030-546334, Verified ORF YIL034C 12.59 1.00 15 1665.5989 1 YIL034C CAP2 SGDID:S000001296,Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches, Chr IX from 290088-289225, reverse complement, Verified ORF YDR064W 13.27 1.00 232 24441.169 1 YDR064W RPS13 SGDID:S000002471,Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins, Chr IV from 579456-579476,580016-580450, Verified ORF YBL015W 22.507 1.00 14 869.5916 1 YBL015W ACH1 SGDID:S000000111,Acetyl-coA hydrolase, primarily localized to mitochondria; required for acetate utilization and for diploid pseudohyphal growth, Chr II from 194125-195705, Verified ORF YLR148W 49.31 0.81 1 22.9643 1 YLR148W PEP3 SGDID:S000004138,Vacuolar peripheral membrane protein that promotes vesicular docking\fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis, forms complex with Pep5p that mediates protein transport to the vacuole, Chr XII from 434642-437398, Verified ORF YML068W 18.83 0.89 4 264.3045 1 YML068W ITT1 SGDID:S000004533,Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins, Chr XIII from 137550-138944, Verified ORF YLR195C 21.57 0.68 1 44.072 1 YLR195C NMT1 SGDID:S000004185,N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction, Chr XII from 543306-541939, reverse complement, Verified ORF YDL089W 18.648 0.99 5 371.0888 1 YDL089W YDL089W SGDID:S000002247,Protein of unknown function; interacts with meiotic division protein Csm1p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery, potential Cdc28p substrate, Chr IV from 296820-298274, Uncharacterized ORF YIL043C 16.339 1.00 18 1540.1107 1 YIL043C CBR1 SGDID:S000001305,Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria, Chr IX from 274925-274071, reverse complement, Verified ORF YDL160C 17.54 1.00 12 956.4374 1 YDL160C DHH1 SGDID:S000002319,Cytoplasmic DExD\H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation, Chr IV from 171931-170411, reverse complement, Verified ORF YFR004W 12.12 1.00 7 807.4215 1 YFR004W RPN11 SGDID:S000001900,Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates, Chr VI from 153388-154308, Verified ORF YCL002C 5.4 0.95 9 2213.4884 1 YCL002C YCL002C SGDID:S000000508,Hypothetical protein, Chr III from 111674-111633,111556-110843, reverse complement, Uncharacterized ORF YDR174W 9.89 1.00 32 4523.3333 1 YDR174W HMO1 SGDID:S000002581,Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase, Chr IV from 812107-812847, Verified ORF YDL054C 8.55 0.82 1 134.0764 1 YDL054C MCH1 SGDID:S000002212,Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport, Chr IV from 361285-359825, reverse complement, Verified ORF YGR231C 9.039 1.00 11 1701.2855 1 YGR231C PHB2 SGDID:S000003463,Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation, Chr VII from 953483-952551, reverse complement, Verified ORF YMR266W 29.07 0.68 3 98.1047 1 YMR266W YMR266W SGDID:S000004879,Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant, Chr XIII from 798517-801378, Uncharacterized ORF YGR034W 6.03 1.00 21 4868.6313 1 YGR034W RPL26B SGDID:S000003266,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA, Chr VII from 555933-555957,556312-556676, Verified ORF YPR081C 27.7 1.00 6 302.8143 1 YPR081C GRS2 SGDID:S000006285,Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for Grs1p; possible pseudogene that is expressed at very low levels, Chr XVI from 703968-702112, reverse complement, Verified ORF YBR026C 16.82 1.00 9 748.0341 1 YBR026C ETR1 SGDID:S000000230,2-enoyl thioester reductase, member of the medium chain dehydrogenase\reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis, Chr II from 294019-292877, reverse complement, Verified ORF YMR125W 38.588 1.00 6 217.3721 1 YMR125W STO1 SGDID:S000004732,Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80, Chr XIII from 517538-517562,517885-520445, Verified ORF YGR054W 23 1.00 10 607.8229 1 YGR054W YGR054W SGDID:S000003286,Eukaryotic initiation factor (eIF) 2A; associates specifically with both 40S subunits and 80 S ribosomes, and interacts genetically with both eIF5b and eIF4E; homologous to mammalian eIF2A, Chr VII from 596697-598625, Verified ORF YML092C 11.44 1.00 32 3910.4691 1 YML092C PRE8 SGDID:S000004557,20S proteasome beta-type subunit, Chr XIII from 86739-85987, reverse complement, Verified ORF YJL105W 20.839 0.98 5 328.7184 1 YJL105W SET4 SGDID:S000003641,Protein of unknown function, contains a SET domain, Chr X from 224973-226655, Verified ORF YKL071W 12.18 0.72 4 330.5598 1 YKL071W YKL071W SGDID:S000001554,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, Chr XI from 304758-305528, Uncharacterized ORF YJR103W 21.304 0.98 7 450.161 1 YJR103W URA8 SGDID:S000003864,Minor CTP synthase isozyme (see also URA7), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis, Chr X from 620669-622363, Verified ORF YGL210W 12.94 0.99 5 534.7808 1 YGL210W YPT32 SGDID:S000003178,GTPase of the Ypt\Rab family, very similar to Ypt31p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi, Chr VII from 93797-94465, Verified ORF YOR191W 74.394 1.00 13 244.2926 1 YOR191W RIS1 SGDID:S000005717,Member of the SWI\SNF family of DNA-dependent ATPases, plays a role in antagonizing silencing during mating-type switching, contains an N-terminal domain that interacts with Sir4p and a C-terminal SNF2 domain, Chr XV from 692476-697335, Verified ORF YGL048C 21.856 1.00 47 3006.2984 1 YGL048C RPT6 SGDID:S000003016,One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle, Chr VII from 411289-410072, reverse complement, Verified ORF YDR027C 37.125 0.65 6 146.8598 1 YDR027C VPS54 SGDID:S000002434,Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; potentially phosphorylated by Cdc28p, Chr IV from 497315-494646, reverse complement, Verified ORF YFL051C 2.32 0.99 1 596.5572 1 YFL051C YFL051C SGDID:S000001843,Putative protein of unknown function; YFL051C is not an essential gene, Chr VI from 30540-30058, reverse complement, Uncharacterized ORF YDL025C 23.469 0.86 6 307.3689 1 YDL025C YDL025C SGDID:S000002183,Protein of unknown function, potentially phosphorylated by Cdc28p, Chr IV from 407203-405341, reverse complement, Uncharacterized ORF YGR169C 19.07 0.78 6 343.0836 1 YGR169C PUS6 SGDID:S000003401,Pseudouridine synthase responsible for modification of cytoplasmic and mitochondrial tRNAs at position 31; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability, Chr VII from 835908-834694, reverse complement, Verified ORF YGR083C 18.497 1.00 10 755.7943 1 YGR083C GCD2 SGDID:S000003315,Delta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression, Chr VII from 646819-644864, reverse complement, Verified ORF YLR293C 7.527 1.00 52 9657.9808 2 YLR293C,YOR185C GSP1 SGDID:S000004284,GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Prp20p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog, Chr XII from 721432-720773, reverse complement, Verified ORF YDR341C 39.916 1.00 141 4938.2947 1 YDR341C YDR341C SGDID:S000002749,Cytoplasmic arginyl-tRNA synthetase, Chr IV from 1153620-1151797, reverse complement, Verified ORF YOL022C 17.81 1.00 8 627.9585 1 YOL022C YOL022C SGDID:S000005382,Protein required for cell viability, Chr XV from 281499-280273, reverse complement, Uncharacterized ORF YGL001C 9.92 1.00 11 1550.1935 1 YGL001C ERG26 SGDID:S000002969,C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis, Chr VII from 496506-495457, reverse complement, Verified ORF YHR031C 40.19 0.99 25 860.9186 1 YHR031C RRM3 SGDID:S000001073,DNA helicase involved in rDNA replication and Ty1 transposition; structurally and functionally related to Pif1p, Chr VIII from 172963-170792, reverse complement, Verified ORF YLR256W-A 8.47 1.00 8 1320.4181 13 YML040W,YPR158C-C,YLR227W-A,YGR027W-A,YDR098C-A,YLR157C-A,YLR256W-A,YOL103W-A,YGR038C-A,YJR026W,YPL257W-A,YDR365W-A,YER137C-A YLR256W-A SGDID:S000007377,TyA Gag protein; the main structural constituent of virus-like particles (VLPs), Chr XII from 651119-652441, transposable_element_gene YLL011W 17.46 0.96 2 153.7311 1 YLL011W SOF1 SGDID:S000003934,Essential subunit of the U3 (box C+D) snRNP complex required for 2' O-methylation of pre-RNA; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p, Chr XII from 127522-128991, Verified ORF YGL090W 22.798 0.88 3 161.887 1 YGL090W LIF1 SGDID:S000003058,Protein involved in DNA double-strand break repair; physically interacts with DNA ligase 4 (Lig4p); homologous to mammalian XRCC4 protein, Chr VII from 343322-344587, Verified ORF YML026C 7.58 1.00 239 44079.1902 2 YDR450W,YML026C RPS18B SGDID:S000004488,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins, Chr XIII from 223828-223782,223380-222987, reverse complement, Verified ORF YLR189C 43.34 1.00 10 322.564 1 YLR189C ATG26 SGDID:S000004179,UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids, involved in autophagy, Chr XII from 534395-530799, reverse complement, Verified ORF YHL020C 16.98 0.87 9 644.6574 1 YHL020C OPI1 SGDID:S000001012,Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance, Chr VIII from 67453-66239, reverse complement, Verified ORF YFL028C 16.188 0.97 1 83.769 1 YFL028C CAF16 SGDID:S000001866,Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation; putative ABC ATPase; interacts with Ssn2p, Ssn3p, and Ssn8p, Chr VI from 80211-79342, reverse complement, Verified ORF YBR256C 10.2 1.00 7 959.4067 1 YBR256C RIB5 SGDID:S000000460,Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway, Chr II from 728097-727381, reverse complement, Verified ORF YNL229C 10.11 0.98 2 271.0252 1 YNL229C URE2 SGDID:S000005173,Nitrogen catabolite repression regulator that acts by inhibition of GLN3 transcription in good nitrogen source; altered form of Ure2p creates [URE3] prion, Chr XIV from 220202-219138, reverse complement, Verified ORF YOR081C 27.236 0.99 9 457.3401 1 YOR081C TGL5 SGDID:S000005607,Triacylglycerol lipase involved in TAG mobilization; localizes to lipid particles; potential Cdc28p substrate, Chr XV from 479190-476941, reverse complement, Verified ORF YLR452C 25.908 0.95 8 410.0951 1 YLR452C SST2 SGDID:S000004444,GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family, Chr XII from 1041364-1039268, reverse complement, Verified ORF YGR279C 10.6 0.99 12 1566.8069 1 YGR279C SCW4 SGDID:S000003511,Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating, Chr VII from 1049964-1048804, reverse complement, Verified ORF YGL123W 12.62 1.00 237 26253.9046 1 YGL123W RPS2 SGDID:S000003091,Protein component of the small (40S) subunit, essential for control of translational accuracy; has similarity to E. coli S5 and rat S2 ribosomal proteins, Chr VII from 277623-278387, Verified ORF YMR005W 16.73 0.67 1 55.9865 1 YMR005W TAF4 SGDID:S000004607,TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate, Chr XIII from 276045-277211, Verified ORF YKL122C 5.46 1.00 14 3584.5967 1 YKL122C SRP21 SGDID:S000001605,Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm, Chr XI from 212642-212139, reverse complement, Verified ORF YML118W 20.588 0.82 1 55.6806 1 YML118W NGL3 SGDID:S000004587,Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p, Chr XIII from 32334-33851, Verified ORF YDL080C 20.79 1.00 4 268.974 1 YDL080C THI3 SGDID:S000002238,Probable decarboxylase, required for expression of enzymes involved in thiamine biosynthesis; may have a role in catabolism of amino acids to long-chain and complex alcohols, Chr IV from 312471-310642, reverse complement, Verified ORF YMR062C 24.34 1.00 8 459.4881 1 YMR062C ECM40 SGDID:S000004666,Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine, Chr XIII from 396378-395053, reverse complement, Verified ORF YDR368W 20.459 1.00 64 4373.2115 1 YDR368W YPR1 SGDID:S000002776,2-methylbutyraldehyde reductase, may be involved in isoleucine catabolism, Chr IV from 1213896-1214834, Verified ORF YEL001C 2.15 0.70 1 455.1604 1 YEL001C YEL001C SGDID:S000000727,Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential, Chr V from 150977-150300, reverse complement, Uncharacterized ORF YJR134C 37.69 0.66 2 48.9612 1 YJR134C SGM1 SGDID:S000003895,Protein of unknown function, required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus, Chr X from 675768-673645, reverse complement, Verified ORF YOL109W 6.16 1.00 74 16794.0684 1 YOL109W ZEO1 SGDID:S000005469,Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p, Chr XV from 110297-110638, Verified ORF YLR179C 9.55 1.00 47 6880.1736 1 YLR179C YLR179C SGDID:S000004169,Protein of unknown function, transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus; YLR179C is not essential, Chr XII from 514715-514110, reverse complement, Uncharacterized ORF YDL034W 4.55 0.73 3 672.88 1 YDL034W YDL034W SGDID:S000002192,Hypothetical protein, Chr IV from 391780-392124, Dubious ORF YAR007C 26.98 1.00 51 2642.6104 1 YAR007C RFA1 SGDID:S000000065,Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination, Chr I from 158621-156756, reverse complement, Verified ORF YPL061W 30.46 1.00 360 16522.5667 1 YPL061W ALD6 SGDID:S000005982,Cytosolic aldehyde dehydrogenase that is activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for the conversion of acetaldehyde to acetate; constitutively expressed, Chr XVI from 432585-434087, Verified ORF YJL060W 22.59 0.84 1 51.9837 1 YJL060W BNA3 SGDID:S000003596,Arylformamidase, involved in biosynthesis of nicotinic acid from tryptophan via kynurenine pathway; potential Cdc28p substrate, Chr X from 323303-324637, Verified ORF YPR062W 5.848 1.00 11 2629.6032 1 YPR062W FCY1 SGDID:S000006266,Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU), Chr XVI from 677162-677638, Verified ORF YLR208W 13.287 1.00 35 3682.5276 1 YLR208W SEC13 SGDID:S000004198,Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p, Sec13p, Sec16p, Sec23p, Sec24p, Sec31p, Sfb2p, and Sfb3p) which is important for the formation of ER to Golgi transport vesicles, Chr XII from 559553-560446, Verified ORF YDR165W 23.55 1.00 25 1484.0687 1 YDR165W TRM82 SGDID:S000002572,Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA, Chr IV from 784868-786202, Verified ORF YMR222C 4.53 0.94 2 580.1824 1 YMR222C FSH2 SGDID:S000004835,Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh1p and Fsh3p, Chr XIII from 716308-715637, reverse complement, Verified ORF YML078W 9.899 0.99 5 699.0669 1 YML078W CPR3 SGDID:S000004543,Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria, Chr XIII from 111002-111550, Verified ORF YMR146C 15.348 1.00 73 6649.3008 1 YMR146C TIF34 SGDID:S000004754,Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation, Chr XIII from 558523-557480, reverse complement, Verified ORF YDR128W 45.639 1.00 5 153.1576 1 YDR128W YDR128W SGDID:S000002535,Hypothetical protein, Chr IV from 709546-712992, Uncharacterized ORF YML085C 13.59 1.00 24 2468.8613 1 YML085C TUB1 SGDID:S000004550,Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules, Chr XIII from 99400-99376,99259-97941, reverse complement, Verified ORF YDR326C 50.758 0.99 4 109.0675 1 YDR326C YDR326C SGDID:S000002734,Hypothetical protein, Chr IV from 1124920-1120604, reverse complement, Uncharacterized ORF YLR330W 18.06 0.97 9 675.7738 1 YLR330W CHS5 SGDID:S000004322,Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p localization, also involved in cell fusion during mating, Chr XII from 787664-789679, Verified ORF YPL198W 11.42 1.00 416 50925.1291 2 YPL198W,YGL076C RPL7B SGDID:S000006119,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2), Chr XVI from 173151-173161,173571-173664,174072-174701, Verified ORF YGL062W 46.899 0.94 3 84.0602 1 YGL062W PYC1 SGDID:S000003030,Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis, Chr VII from 385199-388735, Verified ORF YER080W 42.13 1.00 8 265.4626 1 YER080W YER080W SGDID:S000000882,The authentic, non-tagged protein was localized to the mitochondria, Chr V from 319959-321842, Uncharacterized ORF YHR179W 16.98 1.00 241 19841.9462 1 YHR179W OYE2 SGDID:S000001222,Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism, Chr VIII from 462502-463704, Verified ORF YER057C 4.48 1.00 33 10297.7142 1 YER057C HMF1 SGDID:S000000859,Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro, Chr V from 271124-270735, reverse complement, Verified ORF YCR087C-A 4.768 0.97 2 568.8141 1 YCR087C-A YCR087C-A SGDID:S000007223,Hypothetical protein, Chr III from 264464-264003, reverse complement, Uncharacterized ORF YOR116C 67.014 0.99 12 247.8311 1 YOR116C RPO31 SGDID:S000005642,RNA polymerase III subunit C160, part of core enzyme; similar to bacterial beta-prime subunit, Chr XV from 544146-539764, reverse complement, Verified ORF YBL074C 14.76 0.85 5 402.5385 1 YBL074C AAR2 SGDID:S000000170,Component of the U5 snRNP, required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron, Chr II from 87787-86720, reverse complement, Verified ORF YLR029C 6.18 1.00 93 21037.7546 1 YLR029C RPL15A SGDID:S000004019,Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA, Chr XII from 202591-201977, reverse complement, Verified ORF YLR337C 21.59 1.00 3 194.2555 1 YLR337C VRP1 SGDID:S000004329,Proline-rich, actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP), Chr XII from 805106-802653, reverse complement, Verified ORF YDR060W 49.979 1.00 27 755.2332 1 YDR060W MAK21 SGDID:S000002467,Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein, Chr IV from 570646-573723, Verified ORF YMR155W 10.69 0.76 4 397.5582 1 YMR155W YMR155W SGDID:S000004764,Hypothetical protein, Chr XIII from 568550-570193, Uncharacterized ORF YKL093W 13.38 1.00 7 731.3863 1 YKL093W MBR1 SGDID:S000001576,Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants, Chr XI from 264433-265452, Verified ORF YML088W 20.36 0.99 7 475.8393 1 YML088W UFO1 SGDID:S000004553,F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation, Chr XIII from 92235-94241, Verified ORF YDR195W 26.94 0.98 3 152.5649 1 YDR195W REF2 SGDID:S000002603,RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes, Chr IV from 848596-850197, Verified ORF YDL101C 19.137 1.00 8 584.4145 1 YDL101C DUN1 SGDID:S000002259,Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2\M arrest after DNA damage; also regulates postreplicative DNA repair, Chr IV from 281848-280307, reverse complement, Verified ORF YIL140W 26.55 0.71 2 74.7702 1 YIL140W AXL2 SGDID:S000001402,Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate, Chr IX from 85366-87837, Verified ORF YDL102W 51.224 1.00 13 354.7927 1 YDL102W CDC2 SGDID:S000002260,Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER), Chr IV from 276872-280165, Verified ORF YER008C 52.998 0.88 9 208.9154 1 YER008C SEC3 SGDID:S000000810,Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion, Chr V from 171817-167807, reverse complement, Verified ORF YBR126C 16.45 1.00 7 594.8905 1 YBR126C TPS1 SGDID:S000000330,Synthase subunit of trehalose-6-phosphate synthase\phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway, Chr II from 490386-488899, reverse complement, Verified ORF YBL026W 6.25 0.97 4 867.8738 1 YBL026W LSM2 SGDID:S000000122,Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA, Chr II from 170626-170679,170808-171041, Verified ORF YKL142W 16.94 1.00 27 2228.2056 1 YKL142W MRP8 SGDID:S000001625,Putative mitochondrial ribosomal protein, has similarity to E. coli ribosomal protein S2, Chr XI from 178520-179179, Verified ORF YNR021W 11.73 1.00 7 834.2667 1 YNR021W YNR021W SGDID:S000005304,Hypothetical protein, Chr XIV from 668379-669593, Uncharacterized ORF YGR080W 12.1 0.96 2 221.8302 1 YGR080W TWF1 SGDID:S000003312,Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly, Chr VII from 642014-643012, Verified ORF YIL110W 10.699 0.98 1 128.0524 1 YIL110W YIL110W SGDID:S000001372,Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion mutant exhibits a weak vacuolar protein sorting defect and enhanced resistance to the glucan synthase inhibitor caspofungin, Chr IX from 156042-157175, Uncharacterized ORF YDL141W 27.325 0.91 5 232.7856 1 YDL141W BPL1 SGDID:S000002300,Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation, Chr IV from 203040-205112, Verified ORF YBL055C 22.108 0.99 11 688.6258 1 YBL055C YBL055C SGDID:S000000151,Hypothetical protein, Chr II from 116832-115576, reverse complement, Uncharacterized ORF YDR429C 11 1.00 67 8515.0466 1 YDR429C TIF35 SGDID:S000002837,Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation, Chr IV from 1325293-1324469, reverse complement, Verified ORF YOR004W 10.4 0.87 2 233.8949 1 YOR004W YOR004W SGDID:S000005530,Protein required for cell viability, Chr XV from 333593-334357, Uncharacterized ORF YML010W 44.869 1.00 24 747.7729 1 YML010W SPT5 SGDID:S000004470,Protein that forms a complex with Spt4p and mediates both activation and inhibition of transcription elongation; Spt4p-Spt5p complex also plays a role in pre-mRNA processing, Chr XIII from 247677-250868, Verified ORF YPL191C 8.98 0.82 14 1787.1889 1 YPL191C YPL191C SGDID:S000006112,Hypothetical protein, Chr XVI from 184678-183596, reverse complement, Uncharacterized ORF YMR013C 9.16 1.00 15 2289.2894 1 YMR013C SEC59 SGDID:S000004615,Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation, Chr XIII from 296737-295178, reverse complement, Verified ORF YLL010C 11.45 0.84 3 307.6804 1 YLL010C PSR1 SGDID:S000003933,Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p, Chr XII from 130612-129329, reverse complement, Verified ORF YLR272C 47.96 1.00 12 349.7896 1 YLR272C YCS4 SGDID:S000004262,Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin and silencing at the mating type locus, Chr XII from 687204-683674, reverse complement, Verified ORF YNL104C 20.78 1.00 66 4440.2078 1 YNL